They dropped the 1- and 2-year options the last time I checked with Ellansé, largely because those versions were often persisting longer than their originally stated timelines. This may relate to the biostimulatory response triggered by the presence of these microspheres (PMMA-like in function, though Ellansé’s PCL spheres are bioresorbable), resulting in a collagen response that proved more durable than initially anticipated.
The jury is still out on Ellansé’s true long-term longevity across tissues, but if there’s any silver lining, it appears to be favorable for penile applications... perhaps less so in other applications like the face, where reversibility and predictability tend to matter a bit more...
PMMA is not available in Europe to my knowledge following the discontinuation of Metacrill. Whether any leftover stock still exists (I have no information regarding expiration or shelf-life), Ellansé would arguably be the closest non-permanent analogue currently available.
That said, many patients report notably long retention with Ellansé, which may help explain why FDA approval in the U.S. has proven challenging -- since if you can’t tell a patient with certainty how long it will last, you may end up with a host of issues on your hands (except for penile patients, I’d imagine ?, and this is complete speculation on my part).
I'd reach out to
Androfill
regarding these matters, they are quite familiar with all the aforementioned fillers.
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