TOPIC: Infections, Complications, Risks of PMMA?

@S.O.
Oh good to know. Did you get any treatment and how long did it take to go away?

ndbig1 wrote: @S.O.
Oh good to know. Did you get any treatment and how long did it take to go away?

I did not get any treatment as far as I know. I did go in for a Round 2 & 3, but the doctor did not mention having treated it during those rounds...nor did I remember mentioning it to him at the time.
I believe it just went away very gradually over the course of many months...I started this journey more than 6 months ago, so I suspect maybe 3-4 months for the bumps to really become unnoticeable.

link to an article citing complications seen with PMMA injections with specific applications in the penis.

aestheticfacialenhancement.co.za/faq/49-...late-injections.html

@ S.O. I hope to be as lucky. I will still talk to Dr. C. about it and try Kenalog maybe.

Link from above:

Complications After Polymethylmethacrylate Injections:
Report of 32 Cases
Plastic and Reconstructive Surgery. 2008;121(5):1811-1820.Alessandra Grassi Salles, MD, Priscilla Helena Lotierzo, MD, Rolf Gemperli, MD, J'lio Morais Besteiro, MD, Lu's Carlos Ishida, MD, Rodrigo Pinto Gimenez, MD, Jorge Menezes, MD, Marcus Castro Ferreira, MD.
Over the past 15 years, polymethylmethacrylate (PMMA) injections have been used for soft-tissue augmentation. However, there are insufficient data relating to complications associated with dermal fillers containing PMMA.Salles and colleagues examined 32 patients (average age, 43.6 years) with complications following injection of PMMA fillers. Complications were classified into five groups according to the main presentation: tissue Necrosis, granulomas, chronic inflammatory reactions, lip complications, and infections.
Results:Five patients presented with tissue Necrosis after injection: two male patients had skin and subcutaneous Necrosis of the penis after injection for penile enlargement; one female patient had Necrosis in the right ala and nasal tip after injection to improve nasal tip projection; two female patients had Necrosis of the nasal alae, nasolabial fold, and superior lip after injection for nasolabial fold correction.
Ten patients developed severe granulomas starting 6 to 12 months after PMMA injection.
Ten patients had a chronic inflammatory reaction beginning 1 to 10 years after PMMA injection.
Six patients developed lip complications, including stiffness, lymphedema, and Nodule formation after PMMA injection in the lips.
One patient presented with infection (hyperemia, edema, and pustule formation 1 year after injection).
The authors concluded that complications arising from PMMA injections are rare considering the number of successful cases noted. However, they emphasize that these complications are severe, permanent, and difficult or perhaps impossible to treat.
Therefore, safety guidelines1-2 should be observed when using PMMA for soft-tissue augmentation.

Complications After Polymethylmethacrylate Injections: Report of 32 Cases
Plastic and Reconstructive Surgery. 2008;121(5):1811-1820.Alessandra Grassi Salles, MD, Priscilla Helena Lotierzo, MD, Rolf Gemperli, MD, J'lio Morais Besteiro, MD, Lu's Carlos Ishida, MD, Rodrigo Pinto Gimenez, MD, Jorge Menezes, MD, Marcus Castro Ferreira, MD.
Over the past 15 years, polymethylmethacrylate (PMMA) injections have been used for soft-tissue augmentation. However, there are insufficient data relating to complications associated with dermal fillers containing PMMA.Salles and colleagues examined 32 patients (average age, 43.6 years) with complications following injection of PMMA fillers. Complications were classified into five groups according to the main presentation: tissue Necrosis, granulomas, chronic inflammatory reactions, lip complications, and infections. Results:Five patients presented with tissue Necrosis after injection: two male patients had skin and subcutaneous Necrosis of the penis after injection for penile enlargement; one female patient had Necrosis in the right ala and nasal tip after injection to improve nasal tip projection; two female patients had Necrosis of the nasal alae, nasolabial fold, and superior lip after injection for nasolabial fold correction.
Ten patients developed severe granulomas starting 6 to 12 months after PMMA injection.
Ten patients had a chronic inflammatory reaction beginning 1 to 10 years after PMMA injection.
Six patients developed lip complications, including stiffness, lymphedema, and Nodule formation after PMMA injection in the lips.
One patient presented with infection (hyperemia, edema, and pustule formation 1 year after injection).
The authors concluded that complications arising from PMMA injections are rare considering the number of successful cases noted. However, they emphasize that these complications are severe, permanent, and difficult
or perhaps impossible to treat. Therefore, safety guidelines1-2 should be observed when using PMMA for soft-tissue augmentation.

Corrupt posts have been corrected.

There was a reply from Dr. Almir Nacul (the 1st doctor in Brazil who used the blunt micro-cannula in pmma bioplasty and he taught Dr.C. his technique) in the journal of the american society of plastic surgeons to the article of Dr. Salles which I have mentioned it already in page 10 post no. 141
journals.lww.com/plasreconsurg/fulltext/...methacrylate.79.aspx

In regard of necrosis it will depend on the technique of the doctor, his experience, sharp or blunt micro-cannula, deep or superficial injection and the site of injection (the most dangerous area with any dermal fillers is the glabella)There is an article about this necrosis issue:-
onlinelibrary.wiley.com/doi/10.1111/j.15...006.32052.x/abstract
It has already been mentioned about the possibility of necrosis with all dermal injection even with local anesthesia (e.g. lidocaine) in page 3 post no. 45

@M7 is that what I should have done with the link/article?

I simply posted it so it was readily available. I want prospective PMMA patients to be aware of potential risks. What you did was fine... and appreciated.

@E.P. thanks for the support. I always massage them, usually in the shower and also because they are so present. I don\'t know if they are getting better yet. I think it will take significant change for me to notice. There are also hard areas in the vicinity of the bumps also. I am going to have Dr. C try some methods to resolve it. I am not a panic type person so I will hang in there.

It will be better to have few rounds (e.g. max. 3) of PMMA and reach your target quick and stop than to have >5-6 rounds and the reason for that imo is :-
The PMMA is injected between the outer dartos layer (i.e. the fascia or the muscle just directly under the shaft\'s skin) and the deeper buck\' fascia, when the doctor injects in the following rounds he will inject the beads closer to the Dartos fascia and on top of the old ones and sometimes he will puncture the Dartos fascia many times esp. in the following rounds , and you can have more attachments of the beads to the Dartos fascia and also the skin, so you could have in the following rds small lumps or nodules fixed to the skin ---> thickened-like rough skin).
If you ask any surgeon he will tell you the 1st procedure will be easier for him to dissect under the skin but in Revision cases (imagine if it was the 5th or the 6th time) it will be very difficult to undermine the skin because of the scar from the old surgery, in PMMA penile bioplasty the doctor will also dissect with the micro-cannula underneath the skin and the Dartos fascia and as you repeat this bioplasty many times in different period of time you will have more scar formation and also the beads will be close to the skin and the possibility of PMMA beads\'s fixation to the skin is high.

I have only had one procedure. This is why I think I will go to Dr. Passy and end it one last session. IMO I feel like the 4 session plan adds too much more risk and exposure for possible infection and complications. Plus I finally get to see Rio!!

Hello,I am coming from germany and had an opertion with dr Valter in Rio de Janeiro 3 years ago. The esthetic result after the operation was not good. I had product at the base of the penis, and nothing at the top. I had to stop sexual relations until he operated me a second time (for free), as he noticed the result was not good. Bit still I had to pay for the trip from Europe, and suffered during a whole year without sexual relations.Honestly, after the second operation, the result was ok. I felt relieved. But a year after, progressively, my body started to reject the PMMA (product injected).This means I started to have granulomas, small, average and a big bowls (like a kyst). I had to stop sexual relations again. I talked with my doctor about this and told her the truth, even if I felt ashamed. I saw a Dermatologist, then a surgeon who operated me 3 times to extract the granulomas. I have just had the third operation. I still have to wait for the final result because it is still inflammated. But it was not easy because I had an hemorragy after the first \"extracting\' surgery. The second and third reconstructive went well. It does not hurt. I read on many forums that the PMMA is often rejected after some years. For me, it happened two years after the first operation by Dr Valter.
If you have questions, please ask, thanks